Wiki Author
Mary Jane
Cannabis wiki editor at Cannabivo
Mary Jane writes and edits the Cannabivo wiki, translating cannabinoid, terpene and cannabis-science research into plain-language explainers. She is not a medical professional and the wiki is not medical advice — her job is to represent the sourced literature faithfully, cite where it comes from, and flag what is still uncertain.
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Cannabinoid Receptors CB1 and CB2: Distribution, Signaling, and Drug Targets
Cannabinoid receptors CB1 and CB2 shape intoxication, pain, immunity, and drug response through tissue distribution, signaling bias, and receptor state.
Cannabis Use During Pregnancy and Breastfeeding: Evidence, Risks, and Guidance
Cannabis use during pregnancy and breastfeeding carries real exposure risks: THC crosses the placenta, enters breast milk, and evidence remains mixed.
Hemp vs Marijuana Regulatory Definitions and THC Thresholds: An International Comparison
Hemp vs marijuana laws differ by country and state. Compare 0.3% and 1.0% THC thresholds, Delta-9 vs total THC, THCA rules, and product limits.
Non-CB1/CB2 Molecular Targets of Cannabinoids: TRP Channels, PPARs, GPRs, Serotonin, and NaV Channels
Non-CB1/CB2 molecular targets of cannabinoids include TRP channels, PPARs, GPR55, 5-HT1A, and NaV channels linked to pain, inflammation, and anxiety.
Cannabis Pharmacokinetics: Absorption, Distribution, Metabolism, and Excretion
Cannabis pharmacokinetics varies by route, dose, and formulation. Learn how absorption, metabolism, blood levels, and urine tests differ.
Cannabis Lighting Guide: PPFD, DLI, and Grow Lights
Cannabis lighting guide covering PPFD, DLI, spectrum, HPS vs LED, light cycles, hanging height, canopy uniformity, heat load, and energy cost.
THCA Explained: Chemistry, Decarb, Testing, and Law
THCA explained: how cannabis makes it, how heat converts it to THC, why HPLC matters, and how high-THCA flower fits the 2018 Farm Bill.
Cannabis Testing Guide: Labs, COAs, and Safety Data
Cannabis testing guide covering COAs, potency, pesticides, heavy metals, microbes, HPLC, GC-MS, ISO 17025, and why compliant results can mislead.
Cannabis and Alzheimer’s Disease: THC, CBD, CBN Data
Cannabis and Alzheimer’s disease research shows plausible mechanisms for THC, CBD, and CBN, but human evidence remains limited mainly to agitation trials.
Cannabis Nutrients and Feeding Guide: pH, EC, NPK
Cannabis nutrients and feeding explained with NPK, pH, EC, deficiencies, coco vs hydro vs soil, and evidence on flushing and bloom formulas.
THC-O Acetate: Effects, Safety, Legal Status, Facts
THC-O acetate is a semi-synthetic cannabinoid with uncertain potency, acetate inhalation risks, sparse human data, and unstable legal status.
Cannabis Legalization Overview: Global Legal Status
Cannabis legalization overview covering global legal status, decriminalization vs legalization, medical laws, treaty history, and key reform dates.
Cannabis and Anxiety: THC, CBD, Dose, and Risk Guide
Cannabis and anxiety depend on THC dose, CBD, ratio, route, and setting. Learn the biphasic curve, CBD trials, withdrawal risks, and safer use.
Cannabis Pest and Disease Management IPM Guide
Cannabis pest and disease management guide covering diagnosis, IPM, spider mites, thrips, mildew, root rot, sanitation, and climate control.
THCP Cannabinoid: Effects, Potency, and Legal Status
THCP cannabinoid explained: discovery, seven-carbon structure, potency vs THC, likely effects, research gaps, trace natural levels, and legal status.
Cannabis and Appetite: THC, CB1, and the Munchies
Cannabis and appetite explained: how THC activates CB1 pathways, what evidence supports the munchies, and where terpene and medical claims remain weak.
Cannabis pH and EC: ranges, drift, lockout, fixes
Cannabis pH and EC guide covering soil, coco, and hydro ranges, pH drift, nutrient lockout, water quality, runoff testing, and stage-based EC targets.
THCV Cannabinoid Reference: Effects, Studies, Legality
THCV cannabinoid reference covering structure, CB1 dose-switching, diabetes and Parkinson's studies, African strains, legality, dosing, and effects.
Cannabis and Cancer: Proven Uses vs Unproven Claims
Cannabis and cancer evidence is uneven: symptom relief is better supported than anti-tumor claims. Learn benefits, risks, interactions, and key questions.
Cannabis Pruning and Defoliation Techniques Guide
Cannabis pruning and defoliation techniques explained: topping, FIMing, LST, lollipopping, timing by growth stage, recovery, stress, and mistakes.
THC (Tetrahydrocannabinol): Pharmacology, Effects, and Risks
THC is a partial agonist — weaker than your own endocannabinoids. This pharmacological fact explains its biphasic effects, safety ceiling, and medical uses.
Cannabis and Crohn's Disease: Evidence and Risks
Cannabis and Crohn's disease: learn what human trials show about THC, CBD, symptom relief, inflammation, dosing, risks, and medication interactions.
Cannabis Sexing and Feminization Guide Explained
Learn cannabis sexing and feminization, including male vs female traits, pollen control, and how STS, colloidal silver, and rodelization differ.
Alpha-Pinene Terpene: Effects, THC, Memory, Safety
Alpha-pinene terpene explained with chemistry, memory, THC interaction, bronchodilation, inflammation, GRAS status, and where evidence is limited.
Cannabis and Depression: What the Evidence Shows
Cannabis and depression evidence shows short-term relief for some users, but heavier use, adolescent exposure, CUD, and bipolar risk predict worse outcomes.
Cannabis Soil Guide: pH, Coco, Hydro, and Yield
Cannabis soil guide covering pH, coco coir, hydro, porosity, alkalinity, living soil, containers, transplanting, and how medium shapes yield.
Beta-Caryophyllene: the Only CB2-Binding Terpene
Beta-caryophyllene is a cannabis terpene and dietary cannabinoid that binds CB2, not CB1, with data on inflammation, pain, gut health, and mood.
Cannabis and Diabetes: Blood Sugar, CBD, THC Facts
Cannabis and diabetes research is mixed. Learn how CBD, THC, THCV, and the endocannabinoid system affect blood sugar, insulin, and DKA risk.
Cannabis Training Techniques for Yield and Canopy
Cannabis training techniques explained through canopy architecture, apical dominance, light distribution, airflow, recovery time, and plant-count limits.
Alpha-Bisabolol Terpene: Uses, Safety, and Cannabis
Alpha-bisabolol terpene explained: chamomile source, anti-inflammatory research, skin penetration effects, safety status, and rarity in cannabis.